Think more about special occasions.
Think less about cancer.

PROVENGE is a personalized immunotherapy that activates the immune system to help fight advanced prostate cancer and has been proven to help certain men live longer.

Metastatic castration-resistant prostate cancer (mCRPC) is a form of advanced prostate cancer

When prostate cancer no longer responds to androgen deprivation therapy (also known as ADT or hormone therapy) and spreads to other parts of the body, it is known as mCRPC.

PROVENGE is personal

PROVENGE doctor patient
PROVENGE is the first FDA-approved personalized immunotherapy that is clinically proven to extend life for certain men with mCRPC.
As a personalized immunotherapy, PROVENGE works differently from other cancer treatments, such as chemotherapy or hormone therapy.
PROVENGE is personalized because it’s made from your own immune cells. It empowers your immune system's ability to recognize and remember prostate cancer cells
Similar to a vaccine, PROVENGE works to boost your immune system’s ability to target and attack prostate cancer cells immediately, with effects that last over time

PROVENGE offers many benefits

Proven to extend life
PROVENGE helps certain men with mCRPC live longer.
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Generally mild to moderate side effects
The most common side effects are generally mild to moderate and well tolerated. Some men have experienced serious adverse events while taking PROVENGE.
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Short treatment course
Treatment is completed in 6 appointments over the course of about a month.
PROVENGE infographic

Is PROVENGE right for you?

PROVENGE is indicated for men with prostate cancer who:
Are castrate resistant
Have disease progression on hormone therapy (ADT)
Have testosterone levels that are less than 50 ng/dL
Have been diagnosed with metastatic disease, meaning the cancer has spread from the prostate to other areas, such as bones, lymph nodes, or soft tissue
Are not taking drugs for cancer-related pain
Find a doctor

To find a urologist or oncologist who can administer PROVENGE, enter your ZIP code below.

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PROVENGE is recommended for certain men living with mCRPC

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Financial resources for patients and caregivers
PROVENGE is covered by Medicare and by most private insurance plans.
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Get support
A number of organizations can provide you with information, support, and general resources. Some can also help connect you with men who have advanced prostate cancer.

PROVENGE® (sipuleucel-T) is a prescription medicine used to treat certain men with advanced prostate cancer. PROVENGE is an established cellular immunotherapy and is customized to each individual by using his own immune cells.


Before receiving PROVENGE®, tell your doctor about any medical conditions, including heart or lung problems, or if you have had a stroke.