Is PROVENGE Right For Me?

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PROVENGE is a treatment option for certain men with metastatic castrate resistant prostate cancer.

You may be able to receive PROVENGE therapy if:
  • You are on hormone therapy and have rising PSA levels
  • Your cancer has spread from the prostate to other places, such as your bones
  • You are not taking narcotics for cancer-related pain
 

When is the right time for PROVENGE?

PROVENGE can be a treatment option before chemotherapy. In fact, national cancer guidelines recommend PROVENGE as a first treatment option for advanced prostate cancer for men with few or no cancer-related symptoms (Category 1 recommendation). You can still undergo chemotherapy later on, but with PROVENGE you can get your immune system in the fight against your advanced prostate cancer as soon as possible.

Example of a Possible Prostate Cancer Treatment Path

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Treating Advanced Prostate Cancer

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INDICATION

PROVENGE® (sipuleucel-T) is approved by the FDA as an autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.

IMPORTANT SAFETY INFORMATION

PROVENGE is made from your own immune cells. Your cells will be collected at a cell collection center approximately 3 days before each scheduled infusion of PROVENGE. There can be risks associated with the cell collection process, which you should discuss with your doctor before deciding to begin treatment with PROVENGE.

PROVENGE can cause serious reactions. In controlled clinical trials for the treatment of prostate cancer, serious reactions reported in patients in the PROVENGE group included reactions resulting from the infusion of the drug, which occurred within 1 day of infusion, and strokes. Severe infusion reactions included chills, fever, fatigue, weakness, breathing problems (shortness of breath, decreased oxygen level, and wheezing), dizziness, headache, high blood pressure, muscle ache, nausea, and vomiting. Tell your doctor right away if you have breathing problems, chest pains, racing heart or irregular heartbeats, dizziness, nausea, or vomiting after getting PROVENGE because any of these may be signs of heart or lung problems.

The most common side effects reported with PROVENGE were chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment. For more information, talk with your doctor.

Tell your doctor about all your medical problems including heart problems, lung problems or a history of stroke.

Tell your doctor right away if you get a fever over 100°F, or redness at the cell collection or infusion sites, because any of these may be signs of infection.

Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements.

Tell your doctor about any side effect that concerns you or does not go away.

For more information on PROVENGE, please see the Full Prescribing Information or call 1-800-667-5924.

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