Talk to Your Doctor About PROVENGE

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If you are interested in PROVENGE, it is important to talk to your doctor to find out if the time is right to start your treatment.

Some doctors may not have the facilities needed to administer PROVENGE. If your doctor isn’t equipped to provide PROVENGE, don’t worry, just ask to be referred to a doctor who is able to provide the treatment.

While talking to your doctor, It is important to remember that PROVENGE may not affect your PSA levels. In the PROVENGE clinical trials, the main goal was not to lower PSA levels—it was to extend life. So even if your PSA levels do not go down, PROVENGE may help you live longer.

To locate a doctor that can administer PROVENGE, simply enter your ZIP code in our Doctor Locator.

Talk to your doctor about bone scans

Bone scans provide your doctor with important information regarding the spread of prostate cancer and how the disease is progressing.

When prostate cancer spreads, or becomes metastatic, it usually moves into the bones, the most common area being the spine. This is why bone scans are an important step to take when determining whether or not the time is right for PROVENGE.

It is important to talk to your doctor about getting a bone scan to help determine if your cancer has metastasized. Along with increasing PSA levels, a bone scan can help to give your doctor a better idea of whether or not immunotherapy is an option.

Questions to ask your doctor about PROVENGE

The Doctor Discussion Guide is designed to give you the questions you need when talking to your doctor.


Below are some examples of questions from the discussion guide that will help you at your next doctor’s appointment.

  • What are the advantages of taking PROVENGE?
  • Does PROVENGE have any side effects?
  • How is PROVENGE administered and how long does it take?
  • Do I need to get bone scans or other tests before my course of treatment with PROVENGE?
  • Does your office administer PROVENGE?
    • If not, do you recommend a doctor that does? How can I get started with PROVENGE?

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What Do Doctors Say About PROVENGE?

Watch a video to find out why you should talk to your own doctor about whether PROVENGE is right for you.
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Financial Support Is Available

75% of patients receiving PROVENGE are expected to have minimal to $0 out-of-pocket costs.
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PROVENGE® (sipuleucel-T) is approved by the FDA as an autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.


PROVENGE is made from your own immune cells. Your cells will be collected at a cell collection center approximately 3 days before each scheduled infusion of PROVENGE. There can be risks associated with the cell collection process, which you should discuss with your doctor before deciding to begin treatment with PROVENGE.

PROVENGE can cause serious reactions. In controlled clinical trials for the treatment of prostate cancer, serious reactions reported in patients in the PROVENGE group included reactions resulting from the infusion of the drug, which occurred within 1 day of infusion, and strokes. Severe infusion reactions included chills, fever, fatigue, weakness, breathing problems (shortness of breath, decreased oxygen level, and wheezing), dizziness, headache, high blood pressure, muscle ache, nausea, and vomiting. Tell your doctor right away if you have breathing problems, chest pains, racing heart or irregular heartbeats, dizziness, nausea, or vomiting after getting PROVENGE because any of these may be signs of heart or lung problems.

The most common side effects reported with PROVENGE were chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment. For more information, talk with your doctor.

Tell your doctor about all your medical problems including heart problems, lung problems or a history of stroke.

Tell your doctor right away if you get a fever over 100°F, or redness at the cell collection or infusion sites, because any of these may be signs of infection.

Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements.

Tell your doctor about any side effect that concerns you or does not go away.

For more information on PROVENGE, please see the Full Prescribing Information or call 1-800-667-5924.

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