Talk to Your Doctor About PROVENGE

Share this page

If you are interested in PROVENGE, it is important to talk to your doctor to find out if the time is right to start your treatment.

Some doctors may not have the facilities needed to administer PROVENGE. If your doctor isn’t equipped to provide PROVENGE, don’t worry, just ask to be referred to a doctor who is able to provide the treatment.

While talking to your doctor, It is important to remember that PROVENGE may not affect your PSA levels. In the PROVENGE clinical trials, the main goal was not to lower PSA levels—it was to extend life. So even if your PSA levels do not go down, PROVENGE may help you live longer.

To locate a doctor that can administer PROVENGE, simply enter your ZIP code in our Doctor Locator.

Talk to your doctor about bone scans

Bone scans provide your doctor with important information regarding the spread of prostate cancer and how the disease is progressing.

When prostate cancer spreads, or becomes metastatic, it usually moves into the bones, the most common area being the spine. This is why bone scans are an important step to take when determining whether or not the time is right for PROVENGE.

It is important to talk to your doctor about getting a bone scan to help determine if your cancer has metastasized. Along with increasing PSA levels, a bone scan can help to give your doctor a better idea of whether or not immunotherapy is an option.

Questions to ask your doctor about PROVENGE

The Doctor Discussion Guide is designed to give you the questions you need when talking to your doctor.


Below are some examples of questions from the discussion guide that will help you at your next doctor’s appointment.

  • What are the advantages of taking PROVENGE?
  • Does PROVENGE have any side effects?
  • How is PROVENGE administered and how long does it take?
  • Do I need to get bone scans or other tests before my course of treatment with PROVENGE?
  • Does your office administer PROVENGE?
    • If not, do you recommend a doctor that does? How can I get started with PROVENGE?

Share this page


What Do Doctors Say About PROVENGE?

Watch a video to find out why you should talk to your own doctor about whether PROVENGE is right for you.
View now ›

Financial Support Is Available

75% of patients receiving PROVENGE are expected to have minimal to $0 out-of-pocket costs.
Learn more ›

Get Your Free PROVENGE Jumpstart Kit

Find a PROVENGE Treatment Center


PROVENGE® (sipuleucel-T) is an autologous cellular immunotherapy indicated for the treatment of asymptomatic or minimally symptomatic metastatic castrate-resistant (hormone-refractory) prostate cancer.


Before getting PROVENGE, tell your doctor if you:

  • Have heart problems
  • Have lung problems
  • Have a history of stroke
  • Take any other medicines including prescription and nonprescription drugs, vitamins, and dietary supplements.

What are the possible side effects of PROVENGE

PROVENGE infusion can cause serious reactions.

Tell your doctor right away if you:

  • Have breathing problems, chest pains, racing heart or irregular heartbeats, high or low blood pressure, dizziness, fainting, nausea, or vomiting after getting PROVENGE. Any of these may be signs of heart or lung problems.
  • Develop numbness or weakness on one side of the body, decreased vision in one eye or difficulty speaking. Any of these may be signs of a stroke.
  • Develop symptoms of thrombosis which may include pain and/or swelling of an arm or leg with warmth over the affected area, discoloration of an arm or leg, unexplained shortness of breath or chest pain that worsens on deep breathing.
  • Get a fever over 100°F, or redness or pain at the infusion or collection sites. Any of these may be signs of infection.

The most common side effects of PROVENGE include chills, fatigue, fever, back pain, nausea, joint ache, and headache.

These are not all the possible side effects of PROVENGE treatment. For more information, talk with your doctor.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or

For more information on PROVENGE, please see the Full Prescribing Information or call 1-877-336-3736.

Share this page via e-mail

PROVENGE logo with logo lockup

To share this web page with a friend, please provide the information below. Your friend will receive an e-mail with a link to this page, along with a notification that the request came from you.

All fields are required.

By submitting an e-mail address above, you are requesting that we contact the person you specify here on your behalf. Your name and contact information and your friend’s name and contact information are required, but they will not be used other than to distribute the communication you request. For more information, please see our Privacy Policy.