PROVENGE Benefits
How PROVENGE may help certain men with advanced prostate cancer
PROVENGE is an exciting innovation in the treatment of advanced prostate cancer. The benefits you might receive from PROVENGE include the following:
- PROVENGE may help you live longer
- In a clinical study, PROVENGE extended median survival beyond 2 years
- 25.8 months compared with 21.7 months for patients in the control group (P=0.032)
- A typical treatment of PROVENGE can be completed in about a month
- Treatment is complete after 3 infusionsThe act of putting fluid (usually a medication) into a vein., given approximately every 2 weeks
- The most common side effects are primarily mild or moderate
- These side effects include chills, fatigue, fever, back pain, nausea, joint ache, and headache
In one study of PROVENGE, 1.5% of patients in the PROVENGE group stopped treatment due to side effects.
If you are considering PROVENGE as a treatment option, talk to your doctor.
Next: Side Effects
PROVENGE is made from your own immune cells. Your cells will be collected at a cell collection center approximately 3 days before
each scheduled infusion of PROVENGE. There can be risks associated with the cell collection process, which you should discuss with
your doctor before deciding to begin treatment with PROVENGE.
PROVENGE can cause serious reactions. In controlled clinical trials for the treatment of prostate cancer, serious reactions
reported in patients in the PROVENGE group include reactions resulting from the infusion of the drug, which occurred within 1
day of infusion, and strokes. Severe infusion reactions included chills, fever, fatigue, weakness, breathing problems (shortness
of breath, decreased oxygen level, and wheezing), dizziness, headache, high blood pressure, muscle ache, nausea, and vomiting.
Tell your doctor right away if you have breathing problems, chest pains, racing heart or irregular heartbeats, dizziness, nausea,
or vomiting after getting PROVENGE because any of these may be signs of heart or lung problems.
The most common side effects reported with PROVENGE are chills, fatigue, fever, back pain, nausea, joint ache, and headache. These
are not all the possible side effects of PROVENGE treatment. For more information, talk with your doctor.
Tell your doctor about all your medical problems including heart problems, lung problems or a history of stroke.
Tell your doctor right away if you get a fever over 100°F, or redness at the cell collection or infusion sites,
because any of these may be signs of infection.
Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements.
Tell your doctor about any side effect that concerns you or does not go away.
For more information on PROVENGE, please see the Full Prescribing Information or
call Dendreon ON Call at 1-877-336-3736.