PROVENGE Benefits

PROVENGE is a personalized treatment that collects and reprograms your body’s own immune cells. Talk to your doctor to find out how PROVENGE can help you jumpstart your immune system to attack your prostate cancer. Other benefits of PROVENGE are:

  • PROVENGE has been proven to help men live longer—

    Three years after the start of a clinical trial, more men treated with PROVENGE were alive than men not treated with PROVENGE
    • Median survival was 4.1 months longer for men who received PROVENGE (25.8 months)
      than for men who did not (21.7 months)*
      • – PROVENGE reduced the risk of death by 22.5% for patients in the PROVENGE group*
    • *Individual results may vary.
  • Most side effects of PROVENGE were generally mild to moderate—

    The most common side effects in clinical studies were chills, fatigue, fever, back pain, nausea, joint ache, and headache
    • 1.5% of men discontinued treatment with PROVENGE due to side effects*
  • PROVENGE has a short treatment course—

    Therapy can be completed in about a month with only 6 appointments

 




PROVENGE and PSA Levels

Who Is PROVENGE For?

PROVENGE® (sipuleucel-T) is a prescription medicine that is used to treat certain patients with advanced prostate cancer. PROVENGE is made from your own immune cells.
Find out if PROVENGE could be right for you ›

Financial Support May Be Available

More than 90% of Medicare fee-for-service (FFS) patients receiving PROVENGE are expected to have minimal to no out-of-pocket costs.
Learn more ›

Find a PROVENGE Treatment Center

INDICATION

PROVENGE® (sipuleucel-T) is a prescription medicine that is used to treat certain patients with advanced prostate cancer. PROVENGE is made from your own immune cells.

IMPORTANT SAFETY INFORMATION

  • Before getting PROVENGE, tell your doctor about all your medical problems, including problems with your heart or lungs, or if you have had a stroke
  • Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements
  • PROVENGE is made from your own immune cells, collected approximately 3 days before each scheduled infusion of PROVENGE. The collection is called “leukapheresis” (pronounced loo-kuh-fuh-REE-sis). You will get PROVENGE in 3 intravenous infusions (put into your veins), about 2 weeks apart. Each infusion takes about 60 minutes. You will then be monitored for at least 30 minutes. Your doctor will give you a schedule for your cell collection and infusion appointments. It is very important that you arrive on time for your appointments
  • The most common side effects of PROVENGE include chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment
  • PROVENGE infusion can cause serious reactions. Tell your doctor right away if you:
    • Have breathing problems, chest pains, racing heart or irregular heartbeats, high or low blood pressure, dizziness, fainting, nausea, or vomiting after getting PROVENGE. Any of these may be signs of heart or lung problems
    • Develop numbness or weakness on one side of the body, decreased vision in one eye, or difficulty speaking. Any of these may be signs of a stroke
    • Develop symptoms of thrombosis which may include: pain and/or swelling of an arm or leg with warmth over the affected area, discoloration of an arm or leg, unexplained shortness of breath, chest pain that worsens on deep breathing
    • Get a fever over 100°F, or redness or pain at the infusion or collections sites. Any of these may be signs of infection
  • Tell your doctor about any side effect that concerns you or does not go away. For more information, talk with your doctor

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information.