Treating Advanced Prostate Cancer

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Understanding Prostate Cancer and Treatment Options

If you're a man living with prostate cancer, it's important to know that you're not alone in your fight. Prostate cancer is the most common cancer for men and the National Cancer Institute estimates that over 240,000 people will be diagnosed with prostate cancer this year alone.

Prostate cancer is considered advanced if it has spread outside the prostate gland to other parts of the body. This is also called metastatic prostate cancer.

1 in 6 men will be diagnosed with prostate cancer in his lifetime

About 1 in 6 men will be diagnosed with prostate cancer in his lifetime.

1 in 3 men will have cancer return when treated with surgery or radiation

Of men treated with surgery or radiation, more than 1 in 3 will have their cancer return.

4 in 5 men on hormone therapy for prostate cancer will eventually have their cancer spread to other parts of the body

Of men whose cancer progresses while on hormone therapy, 4 in 5 will eventually have their cancer spread to other parts of the body.*

*Statistic is based on multiple clinical trials of patients treated with hormone therapy whose prostate cancer continued to progress.


Advanced treatment options

Men diagnosed with advanced prostate cancer have a variety of life-extending treatment options to choose from. The choice of treatment depends on the stage of the cancer, as well as your age and overall health. It’s important for you to talk with your doctor to determine the best treatment option for you.

Treatment options may include:

Hormone therapy

Blocks male hormones, such as testosterone, that prostate cancer cells need to grow

Immunotherapy

Activates a patient’s own immune system to seek out and attack prostate cancer

Chemotherapy

Uses chemicals to stop prostate cancer cells from growing

How is PROVENGE different from other prostate cancer treatments?

PROVENGE is an immunotherapy—Immunotherapy works by stimulating the immune cells already in your body to attack prostate cancer cells.

PROVENGE is NOT chemotherapy—Chemotherapy uses chemicals to stop prostate cancer cells from growing.

PROVENGE is NOT a hormone therapy—Hormones are chemicals made by the body that control the activity of certain cells or organs. Hormone therapy in prostate cancer is used to decrease the level of testosterone in the body.

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Talk to Your Doctor

Trying All the Options

Rollin tried radiation and hormonal treatment before discovering PROVENGE.
See Rollin’s story ›

Getting Diagnosed

Don’s prostate cancer diagnosis came as a surprise.
See Don’s story ›

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INDICATION

PROVENGE® (sipuleucel-T) is approved by the FDA as an autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.

IMPORTANT SAFETY INFORMATION

PROVENGE is made from your own immune cells. Your cells will be collected at a cell collection center approximately 3 days before each scheduled infusion of PROVENGE. There can be risks associated with the cell collection process, which you should discuss with your doctor before deciding to begin treatment with PROVENGE.

PROVENGE can cause serious reactions. In controlled clinical trials for the treatment of prostate cancer, serious reactions reported in patients in the PROVENGE group included reactions resulting from the infusion of the drug, which occurred within 1 day of infusion, and strokes. Severe infusion reactions included chills, fever, fatigue, weakness, breathing problems (shortness of breath, decreased oxygen level, and wheezing), dizziness, headache, high blood pressure, muscle ache, nausea, and vomiting. Tell your doctor right away if you have breathing problems, chest pains, racing heart or irregular heartbeats, dizziness, nausea, or vomiting after getting PROVENGE because any of these may be signs of heart or lung problems.

The most common side effects reported with PROVENGE were chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment. For more information, talk with your doctor.

Tell your doctor about all your medical problems including heart problems, lung problems or a history of stroke.

Tell your doctor right away if you get a fever over 100°F, or redness at the cell collection or infusion sites, because any of these may be signs of infection.

Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements.

Tell your doctor about any side effect that concerns you or does not go away.

For more information on PROVENGE, please see the Full Prescribing Information or call 1-800-667-5924.