Treating Advanced Prostate Cancer

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Understanding Prostate Cancer and Treatment Options

If you're a man living with prostate cancer, it's important to know that you're not alone in your fight. Prostate cancer is the most common cancer for men and the National Cancer Institute estimates that over 240,000 people will be diagnosed with prostate cancer this year alone.

Prostate cancer is considered advanced if it has spread outside the prostate gland to other parts of the body. This is also called metastatic prostate cancer.

1 in 6 men will be diagnosed with prostate cancer in his lifetime

About 1 in 7 men in the U.S. will be diagnosed with prostate cancer in his lifetime.*

1 in 3 men will have cancer return when treated with surgery or radiation

Of men treated with surgery or radiation, more than 1 in 3 will
have their cancer return.

4 in 5 men on hormone therapy for prostate cancer will eventually have their cancer spread to other parts of the body

Of men whose cancer progresses while on hormone therapy, 4
in 5
will eventually have their cancer spread to other parts of
the body.

*Based on 2010-2012 data.

Statistic is based on multiple clinical trials of patients treated with hormone therapy whose prostate cancer continued to progress.


Advanced treatment options

Men diagnosed with advanced prostate cancer have a variety of potentially life-extending treatment options to choose from. The choice of treatment depends on the stage of the cancer, as well as your age and overall health. It’s important for you to talk with your doctor to determine which treatment option is best for you.

Treatment options may include:

Hormone therapy

Blocks male hormones, such as testosterone, that prostate cancer cells need to grow

Immunotherapy

Activates a patient’s own immune system to seek out and attack prostate cancer

Chemotherapy

Uses chemicals to stop prostate cancer cells from growing

How is PROVENGE different from other prostate cancer
treatments?

PROVENGE is an immunotherapy—Immunotherapy works by stimulating the immune cells already in your body to attack prostate cancer cells.

PROVENGE is not chemotherapy—Chemotherapy uses chemicals to stop prostate cancer cells from growing.

PROVENGE is not a hormone therapy—Hormones are chemicals made by the body that control the activity of certain cells or organs. Hormone therapy in prostate cancer is used to decrease the level of testosterone in the body.

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Talk to Your Doctor

Who Is PROVENGE For?

PROVENGE® (sipuleucel-T) is a prescription medicine that is used to treat certain patients with advanced prostate cancer. PROVENGE is made from your own immune cells.
Find out if PROVENGE could be right for you ›

Find a PROVENGE Treatment Center

INDICATION

PROVENGE® (sipuleucel-T) is a prescription medicine that is used to treat certain patients with advanced prostate cancer. PROVENGE is made from your own immune cells.

IMPORTANT SAFETY INFORMATION

  • Before getting PROVENGE, tell your doctor about all your medical problems, including problems with your heart or lungs, or if you have had a stroke
  • Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements
  • PROVENGE is made from your own immune cells, collected approximately 3 days before each scheduled infusion of PROVENGE. The collection is called “leukapheresis” (pronounced loo-kuh-fuh-REE-sis). You will get PROVENGE in 3 intravenous infusions (put into your veins), about 2 weeks apart. Each infusion takes about 60 minutes. You will then be monitored for at least 30 minutes. Your doctor will give you a schedule for your cell collection and infusion appointments. It is very important that you arrive on time for your appointments
  • The most common side effects of PROVENGE include chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment
  • PROVENGE infusion can cause serious reactions. Tell your doctor right away if you:
    • Have breathing problems, chest pains, racing heart or irregular heartbeats, high or low blood pressure, dizziness, fainting, nausea, or vomiting after getting PROVENGE. Any of these may be signs of heart or lung problems
    • Develop numbness or weakness on one side of the body, decreased vision in one eye, or difficulty speaking. Any of these may be signs of a stroke
    • Develop symptoms of thrombosis which may include: pain and/or swelling of an arm or leg with warmth over the affected area, discoloration of an arm or leg, unexplained shortness of breath, chest pain that worsens on deep breathing
    • Get a fever over 100°F, or redness or pain at the infusion or collections sites. Any of these may be signs of infection
  • Tell your doctor about any side effect that concerns you or does not go away. For more information, talk with your doctor

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information.

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INDICATION

PROVENGE® (sipuleucel-T) is a prescription medicine that is used to treat certain patients with advanced prostate cancer. PROVENGE is made from your own immune cells.

IMPORTANT SAFETY INFORMATION

  • Before getting PROVENGE, tell your doctor about all your medical problems, including problems with your heart or lungs, or if you have had a stroke
  • Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements
  • PROVENGE is made from your own immune cells, collected approximately 3 days before each scheduled infusion of PROVENGE. The collection is called “leukapheresis” (pronounced loo-kuh-fuh-REE-sis). You will get PROVENGE in 3 intravenous infusions (put into your veins), about 2 weeks apart. Each infusion takes about 60 minutes. You will then be monitored for at least 30 minutes. Your doctor will give you a schedule for your cell collection and infusion appointments. It is very important that you arrive on time for your appointments
  • The most common side effects of PROVENGE include chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment
  • PROVENGE infusion can cause serious reactions. Tell your doctor right away if you:
    • Have breathing problems, chest pains, racing heart or irregular heartbeats, high or low blood pressure, dizziness, fainting, nausea, or vomiting after getting PROVENGE. Any of these may be signs of heart or lung problems
    • Develop numbness or weakness on one side of the body, decreased vision in one eye, or difficulty speaking. Any of these may be signs of a stroke
    • Develop symptoms of thrombosis which may include: pain and/or swelling of an arm or leg with warmth over the affected area, discoloration of an arm or leg, unexplained shortness of breath, chest pain that worsens on deep breathing
    • Get a fever over 100°F, or redness or pain at the infusion or collections sites. Any of these may be signs of infection
  • Tell your doctor about any side effect that concerns you or does not go away. For more information, talk with your doctor

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information.