PROVENGE Treatment Process
Each dose of PROVENGE is personalized by taking
your own blood cells and reprogramming them to jumpstart your immune system. This
section also talks about the importance of PSA levels and the role they play in
the PROVENGE treatment process. Here’s a step-by-step overview of the process:
Step 1: Cell collection
To make each dose, blood will be drawn from your body and passed through a machine
that collects a small portion of your immune cells, along with some platelets and
a small number of red blood cells. The machine returns the rest of the cells and
blood to your body.
Step 2: PROVENGE treatment
Your immune cells are then sent to an FDA-approved manufacturing facility to be
made into a dose of PROVENGE specifically for you.
Each dose of PROVENGE is given about 3 days after your cell collection
procedure, and your appointment will take about 2 hours
The PROVENGE infusion procedure will take place at a different location than your
procedure, usually your physician’s office
After 6 appointments, your treatment with PROVENGE is complete.
As this sample schedule shows, your time commitment for PROVENGE is 6 appointments
over about a month. After these appointments, no future treatments with PROVENGE
The importance of keeping scheduled appointments
It’s important to keep all of your scheduled treatment appointments and arrive prepared.
Your dose of PROVENGE is custom made for you and has a short shelf life. If you
miss an infusion appointment, your personal
dose of PROVENGE will expire and can no longer be used. As a result, you’d have
to repeat the cell collection
procedure so a new custom dose of PROVENGE could be manufactured.
We encourage you to use the calendar inside your Patient Comfort Kit to set reminders
for yourself. You can also ask family members or friends to mark your procedure
dates on their calendars too, to help ensure that you do not miss any appointments.
Important information about PROVENGE and PSA levels
The prostate-specific antigen (PSA)
test is often used to monitor progression of prostate cancer and how effectively
your treatment is controlling the disease. However in the PROVENGE clinical trial,
the main goal was not to lower PSA levels—it was to extend life. So even if your
PSA levels do not go down, PROVENGE may help you live longer.
Changes in PSA levels may not be indicative of how well your PROVENGE treatment is working. Be
sure to talk to your doctor if you have any questions or concerns about your PSA
Preparing for Treatment
More than 90% of Medicare fee-for-service (FFS) patients receiving PROVENGE are expected to have minimal to no out-of-pocket
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