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INDICATION

PROVENGE® (sipuleucel-T) is approved by the FDA as an autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.

IMPORTANT SAFETY INFORMATION

PROVENGE is intended solely for autologous use and is not routinely tested for transmissible infectious diseases.

In controlled clinical trials, serious adverse events reported in the PROVENGE group included acute infusion reactions (occurring within 1 day of infusion) and cerebrovascular events. Severe (Grade 3) acute infusion reactions were reported in 3.5% of patients in the PROVENGE group. Reactions included chills, fever, fatigue, asthenia, dyspnea, hypoxia, bronchospasm, dizziness, headache, hypertension, muscle ache, nausea, and vomiting. No Grade 4 or 5 acute infusion reactions were reported in patients in the PROVENGE group.

The most common adverse events (incidence ≥ 15%) reported in the PROVENGE group were chills, fatigue, fever, back pain, nausea, joint ache, and headache.

Please see the Full Prescribing Information.

Join the Fight Against Prostate Cancer

Dendreon supports all prostate cancer advocates in their efforts to help raise awareness of prostate cancer and improve the lives of those living with prostate cancer. Please click on the organizations displayed to find out what they are doing in support of Prostate Cancer Awareness, including possible events in your community. And, you can show your support for Prostate Cancer Awareness by clicking on the badges to the right to post to your personal site, Twitter page (use 112px x 112px), or Facebook page (use 230px x 65px).

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